Our design is based primarily on an operational risk analysis focusing on several issues: types of risks, design and fit-out of premises, design of specialist facilities, choice of instrumentation, specific prevention and protection measures, ventilation, compressed and/or liquefied gases, supplies and waste, hazard signage, organisation of laboratory safety , use of equipment, handling of chemical substances, work by external personnel, incident management, accident management, changes in the operation and fit-out of the laboratories.